References

This scholarly article represents the established research on the physics and math modeling of microbubble cavitation (Pgs. 2-8 through 2-11, and 2-15 through 2-21).

• http://ftp.rta.nato.int/public//PubFullText/RTO/EN/RTO-EN-AVT-143///EN-AVT-143-02.pdf

This article is on local cavitation suppression using cavitation nuclei preconditioning for precise treatment in histotripsy which is basically using ultrasound as a death ray.

• http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=5935735

This paper discusses the process of cavitation in general terms and presents several useful diagrams to help illustrate the process. It also has an extensive list of references that may be helpful as research for the project.

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/

Current research relevant to the project (the abstract of article is below).

• This paper presents a study that investigates the destructive energy output resulting from hydrodynamic bubbly cavitation in microchannels and its potential use in biomedical applications. The research performed in this study includes results from bubbly cavitation experiments and findings showing the destructive effects of bubbly cavitating flow on selected solid specimens and live cells. The bubbles generated by hydrodynamic cavitation are highly destructive at the surfaces of the target medium on which they are carefully focused. The resulting destructive energy output could be effectively used for biomedical treatments, such as destroying kidney stones (renal calculi) or killing cancer cells. Motivated by this potential, the cavitation damage to cancerous cells and material removal from chalk pieces (which possess similar material properties as some kidney stones) was investigated. Our results showed that cavitation could induce damage both on chalk pieces and leukemia/lymphoma cells. We discovered that hydrodynamic cavitation exposure had early and delayed effects on cancer cell survival. Hence, the potential of hydrodynamic bubbly cavitation generated at the microscale for biomedical treatments was revealed using the microchannel configuration as a microorifice (with an inner diameter of 147 μm and a length of 1.52 cm), which acts as the source of bubbly cavitating flows. This is an article where the different architectural design of microcapsules are discussed.  

• http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=5696746 

This is an article where the different architectural design of microcapsules are discussed.

• http://www.sciencedirect.com.ezproxy2.library.drexel.edu/science/article/pii/S0301562902007871

In this article, microbubble preparation techniques are discussed. 

• http://pubs.rsc.org/en/Content/ArticleLanding/2008/SM/b809517p

Below is the manufacturer link for the Microbubble Contrast Agent.

• http://protechinternational.com/product_info.php?products_id=218 

This site explains the general overview and ideas of encapsulation and drug delivery using ultrasound from the UCL (University College London's) Mechanical Engineering website.

• http://www.mecheng.ucl.ac.uk/research/biomedical-engineering/encapsulation/

The article has some pre-existing solution for some diseases using ultrasound controlled delivery

• http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4747724